Eli Cain established himself as a pivotal collegiate athlete at DePaul University, where he became the first player in program history to achieve 1,400 career points, 350 assists, and 150 three-pointers by 2019. Prior to his collegiate career, Cain honed his skills, accumulating over 2,000 career points at the high school level. He signed with DePaul University on April 20, 2015, and quickly made an impact, earning a spot on the BIG EAST All-Freshman Team in 2016. By 2018, Cain reached another significant milestone, becoming the 50th player in DePaul history to surpass 1,000 career points.
Following his decorated collegiate career, Cain transitioned seamlessly into professional basketball, joining the NBA G League’s Salt Lake City Stars as a dynamic guard. Cains professional journey in the NBA G League has seen him contribute across multiple seasons, demonstrating consistent performance. While with the Salt Lake City Stars, he maintained career averages of 6.3 points, 2.0 rebounds, and 1.7 assists per game. During the 2021-22 season, Cain further expanded his experience by playing for the South Bay Lakers before returning to the Salt Lake City Stars for the 2022-23 and 2023-24 seasons, where he continued to be a valuable asset.
In 2024, Eli Cain broadened his professional footprint internationally, signing with the Caledonia Gladiators. This move positions him to compete in both the United Kingdom Super League Basketball and the prestigious FIBA Europe Cup, further showcasing his adaptability and commitment to top-tier basketball across global leagues. Cain’s continued evolution as a professional player underscores his ability to excel in diverse competitive environments.