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Paolo De Coppi is a leading Consultant Paediatric Surgeon and a prominent figure in stem cell and regenerative medicine, contributing significantly to advancements in treating complex congenital anomalies.
Professor Paolo De Coppi, surgeon at GOSH and NIHR Professor of Paediatric Surgery at UCL Great Ormond Street Institute of Child Health, mentioned in an article about nanodiamonds and hormones used in a rare condition to promote lung growth at birth.
Professor De Coppi's research aims to build and test an artificial oesophagus as a model treatment for paediatric patients with oesophageal atresia. He claims to grow all possible internal organs in his lab at UCL.
Professors Paolo De Coppi and Bobby Gaspar have been named in TIME's inaugural TIME100 Health List, as two of the 100 most influential people in global health.
Paolo De Coppi is a Consultant Paediatric Surgeon at Great Ormond Street Hospital (GOSH), and Reader and Head of Stem Cells and Regenerative Medicine at the UCL Institute of Child Health.
Paediatric surgeon at #GOSH, Professor Paolo De Coppi on the findings of new Lancet paper exploring how best to improve care for newborns.
Official Opening Lecture of the EUPSA Congress in Dubrovnik by Professor Paolo De Coppi, President of EUPSA.
Professor De Coppi has led innovative research in the fields of regenerative medicine and pre and postnatal treatment of congenital conditions, leading to his election as a Fellow of the Academy of Medical Sciences.
Paolo De Coppi serves as a Consultant Paediatric Surgeon at Great Ormond Street Hospital (GOSH) in London. Concurrently, he holds the position of Reader and Head of Stem Cells and Regenerative Medicine at the UCL Institute of Child Health. His academic appointments include Honorary Professor at Katholieke Universiteit Leuven, Belgium, since 2013; Adjunct Assistant Professor at the Wake Forest Institute for Regenerative Medicine in Winston-Salem, North Carolina, since 2009; and Honorary Assistant Professor in Paediatric Surgery at the University of Padua, Italy, since 2005. His work encompasses both advanced surgical procedures for congenital malformations, particularly those utilizing minimally invasive techniques, and extensive research into stem cell applications.
His research has focused on understanding and applying stem cells and tissue engineering to address congenital anomalies. A significant milestone occurred while working with Anthony Atala, M.D., at Boston Children’s Hospital, where he identified the potential of amniotic fluid stem cells for therapeutic purposes. This discovery led to an international patent and was featured on the cover of Nature Biotechnology in January 2007. This work has facilitated new approaches for correcting congenital malformations, with his team demonstrating the ability of these cells to differentiate into various tissues and restore functional activity in animal disease models. His current efforts are directed towards developing reliable methods for the clinical isolation, expansion, and differentiation of stem cells.
In 2010, Mr. De Coppi was part of the team at GOSH that successfully performed the first transplantation of a tissue-engineered trachea on a child. This achievement underscores his practical application of regenerative medicine. He has contributed to over 150 peer-reviewed articles published in journals such as The Lancet, Nature Biotechnology, PNAS, Blood, and FASEB Journal. He has provided supervision to more than 30 research fellows and Ph.D. students and has secured numerous national and international grants for his research. Since 2009, he has served on editorial boards for Paediatric Surgery International, Stem Cell Development, and Fetal and Maternal Medicine Review, and has been Senior Editor for Stem Cell Translational Medicine since 2011, a key publication in translational stem cell research. He co-ordinates the EU Horizon2020 funded stem cell research consortium – INTENS, aiming to create a functional reconstructed bowel for individuals with Short Bowel Syndrome.
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