Melanie Woods made her senior debut at the 2021 World Para Athletics European Championships in Poland, where she competed in four events and secured a fifth-place finish in the T54 800m. Her competitive career commenced in 2019 with participation in the Inter-Spinal Unit Games, followed by joining the Red Star Athletics Club in Glasgow for dedicated training. In 2020, Woods received crucial funding from WheelPower, which enabled her to acquire carbon fiber wheels for her racing chair, a significant advancement that further enhanced her training under the guidance of coach Rodger Harkins and alongside fellow athlete Sammi Kinghorn. Following her impressive senior debut, Woods consistent performance swiftly led to her selection for the Tokyo 2020 Paralympic Games.
This consistent performance continued into 2023, as she participated in the World Para Athletics Championships, securing a tenth-place finish in the 400m T54. Most recently, the 2024 World Para Athletics Championships in Kobe, Japan, saw Woods achieve two formidable fourth-place finishes in the 400m and 1500m categories, alongside a seventh-place finish in the 800m T54. Her unwavering dedication and achievements earned her selection for the 2024 Summer Paralympics in Paris, France, where she further distinguished herself by placing sixth in the T54 800m and eighth in the T54 1500m, cementing her status as a leading Para-athletics wheelchair racer representing Great Britain.