David Regis began his distinguished professional football career in 1988 with Valenciennes FC in France, where he played as a defender for five seasons until 1993. He then transferred to Racing Club de Strasbourg Alsace in 1993, achieving a significant milestone by winning the 1995 UEFA Intertoto Cup with the club. His successful club career continued with moves to RC Lens in 1996 and Karlsruher SC in 1997, where he competed in the prestigious German Bundesliga. Regis later returned to France, joining FC Metz and subsequently Troyes AC, contributing to top-tier European leagues throughout his tenure.
Regiss international career saw him become a key player for the United States national team after his naturalization on May 20, 1998. He received his first cap for the U.S. just three days later, on May 23, 1998, and played in all three matches for the United States in the 1998 FIFA World Cup. Acknowledged for his effectiveness on the field, he was also a member of the U.S.
Continuing his dedication to the sport, Regis served as the Sporting Director for the Martinique national football team in 2017, overseeing strategic development and operations. From 2019 to 2021, he held the role of assistant coach for US Mondorf-les-Bains. Throughout his comprehensive playing career, David Regis accumulated an impressive 440 appearances and scored 15 goals across various elite competitions including Ligue 1, Ligue 2, Bundesliga, Coupe de France, and the UEFA Cup, cementing his legacy as a highly accomplished professional in global football.