During his tenure at East Carolina University from 2013 to 2016, Jones consistently led the team, starting with his freshman year in 2013 where he recorded 62 catches for 604 yards and five touchdowns. His record-breaking 2016 senior season also saw him as a finalist for the prestigious Biletnikoff Award, ultimately earning him first-team All-American and first-team All-AAC honors. Jones transitioned to the professional ranks in 2017, when he was selected by the Buffalo Bills in the second round as the 37th overall pick in the NFL draft, signing a four-year, $6.77 million contract. He played for the Bills from 2017 to 2019, notably leading the team in receiving in 2018 with 56 receptions for 652 yards and seven touchdowns. Following his time in Buffalo, Jones moved to the Oakland/Las Vegas Raiders, where he played from 2019 to 2021. His impactful NFL journey continued with the Jacksonville Jaguars from 2022 to 2023, where he achieved a career-high performance in 2022, recording 82 receptions for 823 yards and five touchdowns. In 2024, Jones further extended his professional career by signing with the Arizona Cardinals, continuing to contribute his receiving prowess in the league. He continues to demonstrate his capabilities as an accomplished wide receiver in the National Football League.