He began as an assistant at Glenville State, followed by a tenure as an assistant coach at Fairmont State, before joining the NBA G League as an assistant for the Maine Red Claws in the 2016-17 season. Mazzulla’s success at the collegiate level led him to the NBA in 2019, joining the Boston Celtics as an assistant coach for three seasons. In September 2022, he was elevated to interim head coach, quickly making an impact by leading the Celtics to a league-best 42-17 record by the NBA All-Star break. His exceptional leadership earned him Eastern Conference Coach of the Month honors for October/November 2022, and he was selected as head coach for Team Giannis for the 2023 NBA All-Star Game.
This victory made him the youngest head coach to win an NBA title since Bill Russell in 1969, following his distinction as the youngest head coach to make the NBA Finals since Russell earlier that year. Mazzulla continues to solidify his legacy with the Boston Celtics, currently holding the highest winning percentage of any NBA coach with over 200 games coached. His impactful leadership was further recognized with an Eastern Conference Coach of the Month award in March 2025. In August 2025, the Celtics reinforced their long-term commitment to Mazzulla, signing him to another multi-year contract extension, underscoring his pivotal role in the franchise’s continued success and future aspirations.